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Somatic glypican 3 (GPC3) mutations in Wilms' tumour

Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. These findings imply a possible role for GPC3 in Wilms' tumo...

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Autori principali: White, G R M, Kelsey, A M, Varley, J M, Birch, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375433/
https://ncbi.nlm.nih.gov/pubmed/12085187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600417
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