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Overexpression of Betaig-h3 gene downregulates integrin α5β1 and suppresses tumorigenicity in radiation-induced tumorigenic human bronchial epithelial cells

Interaction between cell and extracellular matrix plays a crucial role in tumour invasion and metastasis. Using an immortalised human bronchial epithelial (BEP2D) cell model, the study here shows that expression of Betaig-h3 gene, which encodes a secreted adhesion molecule induced by transforming gr...

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Detalhes bibliográficos
Main Authors: Zhao, Y L, Piao, C Q, Hei, T K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375424/
https://ncbi.nlm.nih.gov/pubmed/12085188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600304
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