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Antisense epidermal growth factor receptor RNA transfection in human glioblastoma cells down-regulates telomerase activity and telomere length

Epidermal growth factor receptor is overexpressed and/or amplified in up to 50% of glioblastomas, suggesting an important role of this gene in glial tumorigenesis and progression. In the present study we demonstrated that epidermal growth factor receptor is involved in regulation of telomerase activ...

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Detalhes bibliográficos
Main Authors: Tian, X-X, Pang, JC-S, Zheng, J, Chen, J, To, S S T, Ng, H-K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375350/
https://ncbi.nlm.nih.gov/pubmed/11953893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600244
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