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Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

Healthy colonocytes derive 60–70% of their energy supply from short-chain fatty acids, particularly butyrate. Butyrate has profound effects on differentiation, proliferation and apoptosis of colonic epithelial cells by regulating expression of various genes associated with these processes. We have p...

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Detalhes bibliográficos
Main Authors: Lambert, D W, Wood, I S, Ellis, A, Shirazi-Beechey, S P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375337/
https://ncbi.nlm.nih.gov/pubmed/11953883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600264
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