Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

Healthy colonocytes derive 60–70% of their energy supply from short-chain fatty acids, particularly butyrate. Butyrate has profound effects on differentiation, proliferation and apoptosis of colonic epithelial cells by regulating expression of various genes associated with these processes. We have p...

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Bibliografiske detaljer
Main Authors: Lambert, D W, Wood, I S, Ellis, A, Shirazi-Beechey, S P
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Molecular and Cellular Pathology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375337/
https://ncbi.nlm.nih.gov/pubmed/11953883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600264
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