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Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

Healthy colonocytes derive 60–70% of their energy supply from short-chain fatty acids, particularly butyrate. Butyrate has profound effects on differentiation, proliferation and apoptosis of colonic epithelial cells by regulating expression of various genes associated with these processes. We have p...

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Autori principali: Lambert, D W, Wood, I S, Ellis, A, Shirazi-Beechey, S P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375337/
https://ncbi.nlm.nih.gov/pubmed/11953883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600264
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