Anti-angiogenic effects of the thienopyridine SR 25989 in vitro and in vivo in a murine pulmonary metastasis model

Neovascularisation is a key step in tumour growth and establishment of distant metastases. We have recently demonstrated that the thienopyridine SR 25989 an enantiomer of the anti-aggregant clopidogrel (Plavix®) lacking anti-aggregant activity, inhibits endothelial cell proliferation in vitro by inc...

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Main Authors: Mah-Becherel, M C M, Céraline, J, Deplanque, G, Chenard, M-P, Bergerat, J-P, Cazenave, J-P, Klein-Soyer, C
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2002
Ábhair:
Experimental Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375317/
https://ncbi.nlm.nih.gov/pubmed/11875746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600142
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