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Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects

The anti-tumour effects of thalidomide have been associated with its anti-angiogenic properties. Second generation thalidomide analogues are distinct compounds with enhanced therapeutic potential. Although these compounds are beginning to enter trials for the treatment of cancer there is very little...

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Détails bibliographiques
Auteurs principaux: Dredge, K, Marriott, J B, Macdonald, C D, Man, H-W, Chen, R, Muller, G W, Stirling, D, Dalgleish, A G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376196/
https://ncbi.nlm.nih.gov/pubmed/12402158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600607
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