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Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas

Mutation of the p53 gene plays a critical role in the development of cancer and response to cancer therapy. To analyze the mechanism of cancer development and to improve cancer therapy, it is important to assess which genes are downstream components of p53 in cancers, and whether the expression leve...

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Autori principali: Shinoura, N, Sakurai, S, Shibasaki, F, Asai, A, Kirino, T, Hamada, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375280/
https://ncbi.nlm.nih.gov/pubmed/11870542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600061
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