Dose and schedule-finding study of oral topotecan and weekly cisplatin in patients with recurrent ovarian cancer

Both weekly cisplatin chemotherapy and single agent topotecan have proven to be effective in recurrent ovarian cancer. Preclinical data show synergism between cisplatin and topotecan. Side effects for this combination are drug sequence dependent and predominantly haematologic. Since preclinical data...

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Main Authors: Gelderblom, H, Sparreboom, A, Jonge, M J A de, Loos, W J, Wilms, E, Mantel, M A, Hennis, B, Camlett, I, Verweij, J, Burg, M E L van der
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375148/
https://ncbi.nlm.nih.gov/pubmed/11710824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2014
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