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Using an evolutionary algorithm and parallel computing for haplotyping in a general complex pedigree with multiple marker loci

BACKGROUND: Haplotype reconstruction is important in linkage mapping and association mapping of quantitative trait loci (QTL). One widely used statistical approach for haplotype reconstruction is simulated annealing (SA), implemented in SimWalk2. However, the algorithm needs a very large number of s...

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Bibliografiset tiedot
Päätekijät: Lee, Sang Hong, Van der Werf, Julius HJ, Kinghorn, Brian P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375132/
https://ncbi.nlm.nih.gov/pubmed/18405361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-189
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