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Using an evolutionary algorithm and parallel computing for haplotyping in a general complex pedigree with multiple marker loci

BACKGROUND: Haplotype reconstruction is important in linkage mapping and association mapping of quantitative trait loci (QTL). One widely used statistical approach for haplotype reconstruction is simulated annealing (SA), implemented in SimWalk2. However, the algorithm needs a very large number of s...

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Detalhes bibliográficos
Main Authors: Lee, Sang Hong, Van der Werf, Julius HJ, Kinghorn, Brian P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375132/
https://ncbi.nlm.nih.gov/pubmed/18405361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-189
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