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The Proto-Oncogene Int6 Is Essential for Neddylation of Cul1 and Cul3 in Drosophila
Int6 is a proto-oncogene implicated in various types of cancer, but the mechanisms underlying its activity are not clear. Int6 encodes a subunit of the eukaryotic translation initiation factor 3, and interacts with two related complexes, the proteasome, whose activity is regulated by Int6 in S. pomb...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375110/ https://ncbi.nlm.nih.gov/pubmed/18493598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002239 |
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