Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells

We have sequenced the promoter region of the murine asparagine synthetase gene and examined its methylation profile in the CpG islands of L-asparaginase-sensitive 6C3HED cells (asparagine auxotrophs) and resistant variants (prototrophs). In the former, complete methylation of the CpG island is corre...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Peng, H, Shen, N, Qian, L, Sun, X-L, Koduru, P, Goodwin, L O, Issa, J-P, Broome, J D
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2001
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375082/
https://ncbi.nlm.nih.gov/pubmed/11556848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2000
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares