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A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila
Off-target effects have been demonstrated to be a major source of false-positives in RNA interference (RNAi) high-throughput screens. In this study, we re-assess the previously published transcriptional reporter-based whole-genome RNAi screens for the Wingless and Hedgehog signaling pathways using s...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375041/ https://ncbi.nlm.nih.gov/pubmed/17903264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-9-r203 |
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