ESR1 and EGF genetic variation in relation to breast cancer risk and survival

INTRODUCTION: Oestrogen exposure is a central factor in the development of breast cancer. Oestrogen receptor alpha (ESR1) is the main mediator of oestrogen effect in breast epithelia and has also been shown to be activated by epidermal growth factor (EGF). We sought to determine if common genetic va...

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Detalhes bibliográficos
Main Authors: Einarsdóttir, Kristjana, Darabi, Hatef, Li, Yi, Low, Yen Ling, Li, Yu Qing, Bonnard, Carine, Sjölander, Arvid, Czene, Kamila, Wedrén, Sara, Liu, Edison T, Hall, Per, Humphreys, Keith, Liu, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374971/
https://ncbi.nlm.nih.gov/pubmed/18271972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1861
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