Linkage Disequilibrium Mapping of CHEK2: Common Variation and Breast Cancer Risk

BACKGROUND: Checkpoint kinase 2 (CHEK2) averts cancer development by promoting cell cycle arrest and activating DNA repair in genetically damaged cells. Previous investigation has established a role for the CHEK2 gene in breast cancer aetiology, but studies have largely been limited to the rare 1100...

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Detalhes bibliográficos
Main Authors: Einarsdóttir, Kristjana, Humphreys, Keith, Bonnard, Carine, Palmgren, Juni, Iles, Mark M, Sjölander, Arvid, Li, Yuqing, Chia, Kee Seng, Liu, Edison T, Hall, Per, Liu, Jianjun, Wedrén, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457009/
https://ncbi.nlm.nih.gov/pubmed/16671833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030168
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