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Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
Acute cognitive disorders are common in elderly patients with peripheral infections but it is not clear why. Here we injected old and young mice with Escherichia coli lipopolysaccharide (LPS) to mimic an acute peripheral infection and separated the hippocampal neuronal cell layers from the surroundi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374919/ https://ncbi.nlm.nih.gov/pubmed/17951027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2007.08.014 |
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