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Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses

The segmented structure of the influenza virus genome plays a pivotal role in its adaptation to new hosts and the emergence of pandemics. Despite concerns about the pandemic threat posed by highly pathogenic avian influenza H5N1 viruses, little is known about the biological properties of H5N1 viruse...

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Detalles Bibliográficos
Main Authors: Chen, Li-Mei, Davis, C. Todd, Zhou, Hong, Cox, Nancy J., Donis, Ruben O.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374906/
https://ncbi.nlm.nih.gov/pubmed/18497857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000072
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