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WIN 51711-dependent mutants of poliovirus type 3: evidence that virions decay after release from cells unless drug is present.

Twenty-two spontaneous mutants of the Sabin strain of poliovirus type 3 were selected for drug resistance by plating on HeLa cell monolayers in the presence of WIN 51711, an uncoating inhibitor. When replated in the presence and absence of drug, two classes of mutants were observed; mutants displaye...

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Bibliographic Details
Published in:J Virol
Main Authors: Mosser, A G, Rueckert, R R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8382293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.3.1246-1254.1993
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