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Integration is essential for efficient gene expression of human immunodeficiency virus type 1.

A mutant of human immunodeficiency virus type 1 which carries a frameshift insertion in the integrase/endonuclease region of pol gene was constructed in vitro. Upon transfection into cells, although this mutant exhibited a normal phenotype with respect to expression of gag, pol, and env genes and to...

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Bibliographic Details
Main Authors: Sakai, H, Kawamura, M, Sakuragi, J, Sakuragi, S, Shibata, R, Ishimoto, A, Ono, N, Ueda, S, Adachi, A
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC237481/
https://ncbi.nlm.nih.gov/pubmed/8437208
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