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Human immunodeficiency virus type 1 DNA integration: fine structure target analysis using synthetic oligonucleotides.

The target specificity of DNA strand transfer mediated by human immunodeficiency virus type 1 integrase was examined in vitro with synthetic oligonucleotides. Although insertion occurred at most locations in the target, some sites were preferred over others by at least 15-fold. Changing the nucleoti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hong, T, Murphy, E, Groarke, J, Drlica, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC237472/
https://ncbi.nlm.nih.gov/pubmed/8419642
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