Human immunodeficiency virus type 1 DNA integration: fine structure target analysis using synthetic oligonucleotides.

The target specificity of DNA strand transfer mediated by human immunodeficiency virus type 1 integrase was examined in vitro with synthetic oligonucleotides. Although insertion occurred at most locations in the target, some sites were preferred over others by at least 15-fold. Changing the nucleoti...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Hong, T, Murphy, E, Groarke, J, Drlica, K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8419642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.1127-1131.1993
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