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Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts
Multidrug resistance (MDR) and more specifically the expression of P-glycoprotein (Pgp) have been studied extensively in vitro. Unfortunately, it appears that the predictive value of MDR recognized in vitro is mostly an incorrect measure to determine the responsiveness of a particular tumour in the...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374672/ https://ncbi.nlm.nih.gov/pubmed/10970695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1373 |
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