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Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts

Multidrug resistance (MDR) and more specifically the expression of P-glycoprotein (Pgp) have been studied extensively in vitro. Unfortunately, it appears that the predictive value of MDR recognized in vitro is mostly an incorrect measure to determine the responsiveness of a particular tumour in the...

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Autors principals: Kolfschoten, G M, Hulscher, T M, Pinedo, H M, Boven, E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374672/
https://ncbi.nlm.nih.gov/pubmed/10970695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1373
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