Inhibition of aromatase activity and expression in MCF-7 cells by the chemopreventive retinoid N -(4-hydroxy-phenyl)-retinamide

The effect of the chemopreventive synthetic retinoid N -(4-hydroxyphenyl)-retinamide (4-HPR) on aromatase activity and expression was examined. 4-HPR caused a dose-dependent inhibition of aromatase activity in microsomes isolated from JEG-3 human placental carcinoma cells. The kinetics of inhibition...

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Hlavní autoři: Ciolino, H P, Wang, T T Y, Sathyamoorthy, N
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374555/
https://ncbi.nlm.nih.gov/pubmed/10917548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1269
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