Induction of the oxidative catabolism of retinoid acid in MCF-7 cells.

Cytochrome P450-dependent oxidation is a pathway for all-trans-retinoic acid (all-trans-RA) catabolism. Induction of this catabolic pathway was studied in MCF-7 breast cancer cells. MCF-7 cells showed low constitutive all-trans-RA catabolism. Concentration-dependent induction was obtained by preincu...

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Bibliographic Details
Main Authors: Krekels, M. D., Verhoeven, A., van Dun, J., Cools, W., Van Hove, C., Dillen, L., Coene, M. C., Wouters, W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222791/
https://ncbi.nlm.nih.gov/pubmed/9099955
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