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Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila

Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress conditions associated with aging and neurodegeneration,...

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Bibliografske podrobnosti
Main Authors: Muffat, Julien, Walker, David W., Benzer, Seymour
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374552/
https://ncbi.nlm.nih.gov/pubmed/18458334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800896105
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