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Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant

Oxidative stress is implicated as a major cause of aging and age-related diseases, such as Parkinson's and Alzheimer's, as well as ischemia-reperfusion injury in stroke. The mitochondrial electron transport chain is the principal source of reactive oxygen species within cells. Despite cons...

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Detalhes bibliográficos
Main Authors: Walker, David W., Hájek, Petr, Muffat, Julien, Knoepfle, Dan, Cornelison, Stephanie, Attardi, Giuseppe, Benzer, Seymour
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618815/
https://ncbi.nlm.nih.gov/pubmed/17056719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607918103
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