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Mutations in or near the fusion peptide of the influenza virus hemagglutinin affect an antigenic site in the globular region.

We previously described a monoclonal antibody (Y8-10C2) that binds influenza virus hemagglutinin (HA) monomers but not native trimers. In this study, we demonstrated that Y8-10C2 binds to the globular domain of HA and found evidence that its epitope is located at the interface of adjacent subunits....

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Udgivet i:J Virol
Principais autores: Yewdell, J W, Taylor, A, Yellen, A, Caton, A, Gerhard, W, Bächi, T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.2.933-942.1993
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