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Mutations in or near the fusion peptide of the influenza virus hemagglutinin affect an antigenic site in the globular region.

We previously described a monoclonal antibody (Y8-10C2) that binds influenza virus hemagglutinin (HA) monomers but not native trimers. In this study, we demonstrated that Y8-10C2 binds to the globular domain of HA and found evidence that its epitope is located at the interface of adjacent subunits....

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Détails bibliographiques
Auteurs principaux: Yewdell, J W, Taylor, A, Yellen, A, Caton, A, Gerhard, W, Bächi, T
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC237447/
https://ncbi.nlm.nih.gov/pubmed/7678310
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