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Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis
INTRODUCTION: High mobility group box chromosomal protein 1 (HMGB1) is a nuclear protein that acts as a pro-inflammatory mediator following extracellular release. The protein is aberrantly expressed extracellularly in the settings of clinical and experimental synovitis. Therapy based on HMGB1 antago...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374449/ https://ncbi.nlm.nih.gov/pubmed/18179697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2347 |
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