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Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status
Biological parameters influencing the response of human colorectal cancers (CRCs) to CPT-11, a topoisomerase 1 (top1) inhibitor, were investigated using a panel of nine CRCs xenografted into nude mice. CRC xenografts differed in their p53 status (wt or mut) and in their microsatellite instability ph...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374412/ https://ncbi.nlm.nih.gov/pubmed/10732766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.1019 |
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