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Analysis of radon-associated squamous cell carcinomas of the lung for ap53 gene hotspot mutation

Squamous cell lung carcinomas (SCC) from former employees of the Wismut uranium mining company (Saxony, Germany) were obtained from the Stollberg Archive in order to screen for p53 tumour suppressor gene codon 249 arg→met hotspot mutations, a putative molecular bio-dosimeter of alpha-particle (radon...

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Détails bibliographiques
Auteurs principaux: Yang, Q, Wesch, H, Mueller, K-M, Bartsch, H, Wegener, K, Hollstein, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374385/
https://ncbi.nlm.nih.gov/pubmed/10732742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.1999.0995
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