Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in tumour progression and metastasis. In this study, we investigated the in vitro and in vivo expression patterns of MMP-1, MMP-2, MMP-3, MMP-9, TIMP-1 and TIMP-2 mRNA and protein in a previously described human melano...

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Bibliographic Details
Main Authors: Hofmann, U B, Westphal, J R, Waas, E T, Zendman, A J W, Cornelissen, I M H A, Ruiter, D J, Muijen, G N P van
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1999
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374291/
https://ncbi.nlm.nih.gov/pubmed/10555745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690763
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