Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in tumour progression and metastasis. In this study, we investigated the in vitro and in vivo expression patterns of MMP-1, MMP-2, MMP-3, MMP-9, TIMP-1 and TIMP-2 mRNA and protein in a previously described human melano...

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Dettagli Bibliografici
Autori principali: Hofmann, U B, Westphal, J R, Waas, E T, Zendman, A J W, Cornelissen, I M H A, Ruiter, D J, Muijen, G N P van
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1999
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374291/
https://ncbi.nlm.nih.gov/pubmed/10555745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690763
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