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Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis

Tumour cells exposed to hypoxia have been shown to up-regulate the expression of vascular endothelial growth factor (VEGF). The purpose of the present work was to investigate whether hypoxia-induced VEGF up-regulation can result in increased metastatic efficiency of human melanoma cells. Two melanom...

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Detalhes bibliográficos
Main Authors: Rofstad, E K, Danielsen, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374267/
https://ncbi.nlm.nih.gov/pubmed/10468285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690586
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