Binding of Phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography

Human angiogenin (Ang) is an unusual homolog of bovine pancreatic RNase A that utilizes its ribonucleolytic activity to induce the formation of new blood vessels. The pyrimidine-binding site of Ang was shown previously to be blocked by glutamine 117, indicating that Ang must undergo a conformational...

Full description

Saved in:
Bibliographic Details
Main Authors: Leonidas, Demetres D., Chavali, Gayatri B., Jardine, Anwar M., Li, Songlin, Shapiro, Robert, Acharya, K. Ravi
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374093/
https://ncbi.nlm.nih.gov/pubmed/11468363
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items