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A partially folded intermediate species of the β-sheet protein apo-pseudoazurin is trapped during proline-limited folding

The folding of apo-pseudoazurin, a 123-residue, predominantly β-sheet protein with a complex Greek key topology, has been investigated using several biophysical techniques. Kinetic analysis of refolding using far- and near-ultraviolet circular dichroism (UV CD) shows that the protein folds slowly to...

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Main Authors: Reader, John S., Van Nuland, Nico A. J., Thompson, Gary S., Ferguson, Stuart J., Dobson, Christopher M., Radford, Sheena E.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374025/
https://ncbi.nlm.nih.gov/pubmed/11369860
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