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Optimization of binding electrostatics: Charge complementarity in the barnase-barstar protein complex

Theoretical and experimental studies have shown that the large desolvation penalty required for polar and charged groups frequently precludes their involvement in electrostatic interactions that contribute strongly to net stability in the folding or binding of proteins in aqueous solution near room...

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Detalhes bibliográficos
Main Authors: lee, Lee-Peng, Tidor, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373948/
https://ncbi.nlm.nih.gov/pubmed/11266622
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