Phosphorylated Epidermal Growth Factor Receptor on Tumor-Associated Endothelial Cells Is a Primary Target for Therapy with Tyrosine Kinase Inhibitors

We determined whether phosphorylated epidermal growth factor receptor (EGFR) expressed on tumor-associated endothelial cells is a primary target for therapy with EGFR tyrosine kinase inhibitors (TKIs). Human colon cancer cells SW620CE2 (parental) that do not express EGFR or human epidermal growth fa...

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Detalhes bibliográficos
Main Authors: Kuwai, Toshio, Nakamura, Toru, Sasaki, Takamitsu, Kim, Sun-Jin, Fan, Dominic, Villares, Gabriel J, Zigler, Maya, Wang, Hua, Bar-Eli, Menashe, Kerbel, Robert S, Fidler, Isaiah J
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373870/
https://ncbi.nlm.nih.gov/pubmed/18472966
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