Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

We conducted a Phase I clinical trial investigating the biologic activity of vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor in patients with metastatic melanoma. Immunization sites were intensely infiltrated with T l...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., Hodi, F. Stephen, Liebster, Laura, Lam, Prudence, Mentzer, Steven, Singer, Samuel, Tanabe, Kenneth K., Cosimi, A. Benedict, Duda, Rosemary, Sober, Arthur, Bhan, Atul, Daley, John, Neuberg, Donna, Parry, Gordon, Rokovich, Joseph, Richards, Laurie, Drayer, Jan, Berns, Anton, Clift, Shirley, Cohen, Lawrence K., Mulligan, Richard C., Dranoff, Glenn
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1998
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13141
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