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Mechanically unfolding proteins: The effect of unfolding history and the supramolecular scaffold

The mechanical resistance of a folded domain in a polyprotein of five mutant I27 domains (C47S, C63S I27)(5)is shown to depend on the unfolding history of the protein. This observation can be understood on the basis of competition between two effects, that of the changing number of domains attemptin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zinober, Rebecca C., Brockwell, David J., Beddard, Godfrey S., Blake, Anthony W., Olmsted, Peter D., Radford, Sheena E., Smith, D. Alastair
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373742/
https://ncbi.nlm.nih.gov/pubmed/12441375
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