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Modifying specificity of antidigoxin antibodies using insertional mutagenesis

Certain antibodies (Abs) elicited using the cardiac glycoside digoxin (digoxigenin tridigitoxoside) bind preferentially to analogs that differ from digoxin by substitutions on the cardenolide rings, the lactone, or by the presence or absence of attached sugars. Antibody 26–10 binds equally well to d...

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Bibliografische gegevens
Hoofdauteurs: Krykbaev, Rustem A., Tsantili, Panayota, Jeffrey, Philip D., Margolies, Michael N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373741/
https://ncbi.nlm.nih.gov/pubmed/12441388
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