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The dimeric dihydroorotate dehydrogenase A from Lactococcus lactis dissociates reversibly into inactive monomers

The flavoenzyme dihydroorotate dehydrogenase A from Lactococcus lactis is a homodimeric protein of 311 residues/subunit, and the two active sites are positioned at a distance from the dimer interface. To promote formation of the monomeric form of the enzyme, we changed the residues involved in forma...

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Detalhes bibliográficos
Main Authors: Ottosen, Mette Brimheim, Björnberg, Olof, Nørager, Sofie, Larsen, Sine, Palfey, Bruce Allan, Jensen, Kaj Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373731/
https://ncbi.nlm.nih.gov/pubmed/12381841
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