Topological investigation of amyloid fibrils obtained from β2-microglobulin

Amyloid fibrils of patients treated with regular hemodialysis essentially consists of β2-microglobulin (β2-m) and its truncated species ΔN6β2-m lacking six residues at the amino terminus. The truncated fragment has a more flexible three-dimensional structure and constitutes an excellent candidate fo...

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Main Authors: Monti, Maria, Principe, Serena, Giorgetti, Sofia, Mangione, Palma, Merlini, Gianpaolo, Clark, Anne, Bellotti, Vittorio, Amoresano, Angela, Pucci, Piero
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373708/
https://ncbi.nlm.nih.gov/pubmed/12237458
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