A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge.
We have previously demonstrated that induction of antiviral cytotoxic T lymphocytes (CTL), in the absence of antiviral antibodies, can confer protection against a lethal-dose virus challenge. Here we extend those findings as follows. First, three discrete viral CTL epitopes expressed from minigenes...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7677954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.1.348-352.1993 |
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