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Design of an optimal Chebyshev-expanded discrimination function for globular proteins

We describe the construction of a scoring function designed to model the free energy of protein folding. An optimization technique is used to determine the best functional forms of the hydrophobic, residue-residue and hydrogen-bonding components of the potential. The scoring function is expanded by...

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Autors principals: Fain, Boris, Xia, Yu, Levitt, Michael
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373672/
https://ncbi.nlm.nih.gov/pubmed/12142455
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