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The effect of prime-site occupancy on the hepatitis C virus NS3 protease structure
We recently reported a new class of inhibitors of the chymotrypsin-like serine protease NS3 of the hepatitis C virus. These inhibitors exploit the binding potential of the S` site of the protease, which is not generally used by the natural substrates. The effect of prime-site occupancy was analyzed...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2373603/ https://ncbi.nlm.nih.gov/pubmed/12192066 |
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