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Analysis of serine proteinase–inhibitor interaction by alanine shaving

We analyzed the energetic importance of residues surrounding the hot spot (the P(1) position) of bovine pancreatic trypsin inhibitor (BPTI) in interaction with two proteinases, trypsin and chymotrypsin, by a procedure called molecular shaving. One to eight residues of the structural epitope, compose...

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Detalhes bibliográficos
Main Authors: Buczek, Olga, Koscielska-Kasprzak, Katarzyna, Krowarsch, Daniel, Dadlez, Michał, Otlewski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373526/
https://ncbi.nlm.nih.gov/pubmed/11910024
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