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Binding specificity and the ligand dissociation process in the E. coli biotin holoenzyme synthetase

The binding of the Escherichia coli biotin holoenzyme synthetase to the two ligands, biotin and bio-5`-AMP, is coupled to disorder-to-order transitions in the protein. In the structure of the biotin complex, a "glycine-rich" loop that is disordered in the apo-enzyme is folded over the liga...

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Bibliografski detalji
Glavni autori: Kwon, Keehwan, Streaker, Emily D., Beckett, Dorothy
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373468/
https://ncbi.nlm.nih.gov/pubmed/11847279
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