Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane

Heparin-binding EGF-like growth factor (HB-EGF) is synthesized as a type I transmembrane protein (proHB-EGF) and expressed on the cell surface. The ectodomain shedding of proHB-EGF at the extracellular region on the plasma membrane yields a soluble EGF receptor ligand and a transmembrane-cytoplasmic...

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Detalhes bibliográficos
Main Authors: Hieda, Miki, Isokane, Mayumi, Koizumi, Michiko, Higashi, Chiduru, Tachibana, Taro, Shudou, Masachika, Taguchi, Tomohiko, Hieda, Yohki, Higashiyama, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373455/
https://ncbi.nlm.nih.gov/pubmed/18299347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710022
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